7 Types of Drugs That May Lower Your Sex Drive

7 Types of Drugs That May Lower Your Sex Drive

You’ve likely heard about drugs that can improve the sex drive, but there are actually some medications that can reduce it. Do you find that you’re less interested in sex than you would like to be? The issue might be in your medicine cabinet. Be sure to speak with your doctor about possible alternatives if you think medication may be to blame. Read on to learn about medications that have been known to reduce the libido.

Certain Antidepressants

Selective serotonin reuptake inhibitors (SSRIs) such as Zoloft and Prozac improve the mood by raising serotonin, but they can also kill your sex drive. Tricyclic antidepressants, such as Elavil, which are not used as often these days, can also decrease the libido. There are other options as far as antidepressants go, and your doctor may be able to make adjustments for you. Be sure to ask about your options.


OTC antihistamines such as Benadryl (diphenhydramine) and Chlor-Trimeton (chlorpheniramine) can ease allergy symptoms, but also affect your sex drive temporarily. The solution may be to carefully time when you take these drugs. “Many of these drugs do not last 24 hours and certainly their side effects don’t,” says Allison Dering-Anderson, Pharm.D. “Antihistamines should be cleared in eight hours in younger and healthier patients.” Antihistamines are also frequently found in combination cough and cold medicines, so be sure to read the label carefully.

Birth Control Pills

Oral contraceptives may affect libido because they can lower levels of sex hormones, including testosterone. Speak with your doctor about alternatives if your sex drive is being negatively affected by the pill you’re taking.

Anti-Seizure Drugs

Drugs such as Tegretol that are used for people who have seizures and some people with Bipolar Disorder can reduce sexual desire. These types of drugs prevent impulses from traveling along the nerve cells, which is the issue when it comes to sex drive because an orgasm is similar to a seizure, so medications that dampen nerve impulses can also reduce sensations that bring pleasure.

Medical Marijuana

Marijuana is not approved for medical purposes in every state, but it can have a “significant negative impact both on libido and on ability to perform,” says Dering-Anderson.

These can work wonders when it comes to pain relief, but can lower libido as well. Studies show that opioids such as Percocet, Vicodin, and OxyContin can lower testosterone levels, which affects the libido.

Beta Blockers 
Millions of Americans use beta blockers such as metoprolol and propranolol for their heart, but it doesn’t necessarily benefit their sex lives. Fortunately, there are a lot of beta blockers on the market, which lower blood pressure in different ways. Speak with your doctor about finding one that will work for you.



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